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acetyl CoA biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
malonate_semialdehyde + CoA + NAD+ <=> acetyl-CoA + CO2 + NADH 1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
1.2.1.27 methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
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NADP+ + H2O + malonate_semialdehyde <=> malonate + NADPH + H+ 1.2.1.15 malonate-semialdehyde dehydrogenase
1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
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CoA + acetate + ATP <=> phosphate + acetyl-CoA + ADP 6.2.1.1 acetate---CoA ligase
6.2.1.13 acetate---CoA ligase (ADP-forming)
6.2.1.B11
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acetyl-CoA + malonate <=> acetate + malonyl-CoA 2.1.3.10 malonyl-S-ACP:biotin-protein carboxyltransferase
2.8.3.3 malonate CoA-transferase
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H2O + acetyl-CoA <=> H+ + acetate + CoA 2.3.1.16 acetyl-CoA C-acyltransferase
2.3.1.226 carboxymethylproline synthase
2.3.1.31 homoserine O-acetyltransferase
2.3.3.10 hydroxymethylglutaryl-CoA synthase
2.3.3.13 2-isopropylmalate synthase
3.1.2.1 acetyl-CoA hydrolase
3.1.2.17 (S)-methylmalonyl-CoA hydrolase
3.1.2.18 ADP-dependent short-chain-acyl-CoA hydrolase
3.1.2.20 acyl-CoA hydrolase
3.1.2.23 4-hydroxybenzoyl-CoA thioesterase
3.1.2.25 phenylacetyl-CoA hydrolase
3.1.2.29 fluoroacetyl-CoA thioesterase
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acetyl-CoA + enzyme_N6-(dihydrolipoyl)lysine <=> CoA + enzyme_N6-(S-acetyldihydrolipoyl)lysine 2.3.1.12 dihydrolipoyllysine-residue acetyltransferase
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H+ + malonyl-CoA <=> CO2 + acetyl-CoA 2.3.1.226 carboxymethylproline synthase
2.3.1.74 chalcone synthase
4.1.1.87 malonyl-S-ACP decarboxylase
4.1.1.9 malonyl-CoA decarboxylase
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Visualization of the pathway